nectin-3 antibody (Internal Region)

Catalog No. ABIN7218058

This anti-nectin-3 antibody is a Rabbit Polyclonal antibody detecting nectin-3 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for nectin-3 antibody (Internal Region) (ABIN7218058)

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This nectin-3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-nectin-3 Antibody

Binding Specificity: Internal Region

Purpose: Nectin 3 Polyclonal Antibody

Specificity: Nectin 3 Polyclonal Antibody detects endogenous levels of Nectin 3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Nectin 3

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for nectin-3

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Alternative Name: Nectin 3

Background: Rabbit Anti-Nectin 3 Polyclonal Antibody,PVRL3, PRR3, Poliovirus receptor-related protein 3, CDw113, Nectin-3, CD113,NECTIN3 encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants.,Poliovirus receptor-related protein 3

Molecular Weight: observerd band 60kDa

Gene ID: 25945

UniProt: Q9NQS3

Pathways: Cell-Cell Junction Organization