ORC3 antibody
Quick Overview for ORC3 antibody (ABIN7230404)
Target
See all ORC3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- ORC3 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of ORC3 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human ORC3 protein
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))
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Alternative Name
- ORC3
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Background
- Rabbit Anti-ORC3 Polyclonal Antibody,Origin recognition complex subunit 3, Origin recognition complex subunit Latheo,The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. Origin Recognition Complex Subunit 3 encoded by ORC3 is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.,ORC3
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Molecular Weight
- observerd band 78kDa
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Gene ID
- 23595
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UniProt
- Q9UBD5
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Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Feeding Behaviour, Synthesis of DNA
Target
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