PANK2 antibody
Quick Overview for PANK2 antibody (ABIN7230484)
Target
See all PANK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- PANK2 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of PANK2 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human PANK2 protein
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PANK2 (Pantothenate Kinase 2 (PANK2))
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Alternative Name
- PANK2
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Background
- Rabbit Anti-PANK2 Polyclonal Antibody,Pantothenate kinase 2, mitochondrial, hPanK2, Pantothenic acid kinase 2,PANK2 gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms.,PANK2
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Molecular Weight
- observerd band 62kDa
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Gene ID
- 80025
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UniProt
- Q9BZ23
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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