PPIF antibody (AA 60-140)
Quick Overview for PPIF antibody (AA 60-140) (ABIN7214408)
Target
See all PPIF AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 60-140
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Purpose
- Cyclophilin F Polyclonal Antibody
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Specificity
- Cyclophilin F Polyclonal Antibody detects endogenous levels of Cyclophilin F protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human Cyclophilin F at AA range: 60-140
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PPIF (Peptidylprolyl Isomerase F (PPIF))
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Alternative Name
- Cyclophilin F
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Background
- Rabbit Anti-Cyclophilin F Polyclonal Antibody,PPIF, CYP3, Peptidyl-prolyl cis-trans isomerase F, mitochondrial, PPIase F, Cyclophilin F, Rotamase F,Peptidylprolyl isomerase F encoded by PPIF is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.,Peptidyl-prolyl cis-trans isomerase F mitochondrial
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Molecular Weight
- observerd band 22kDa
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Gene ID
- 10105
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UniProt
- P30405
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Pathways
- Proton Transport, Negative Regulation of intrinsic apoptotic Signaling, Negative Regulation of Transporter Activity
Target
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