PF4 antibody (AA 51-100)

Catalog No. ABIN7230600

This anti-PF4 antibody is a Rabbit Polyclonal antibody detecting PF4 in ELISA and IHC (p). Suitable for Human and Rat.

Quick Overview for PF4 antibody (AA 51-100) (ABIN7230600)

Target: PF4 (Platelet Factor 4 (PF4))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PF4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PF4 Antibody

Binding Specificity: AA 51-100

Purpose: PF-4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PF-4

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PF-4 protein at AA range: 51-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PF4

Target: PF4 (Platelet Factor 4 (PF4))

Alternative Name: PF-4

Background: Rabbit Anti-PF-4 Polyclonal Antibody,Platelet factor 4, PF-4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A,PF-4 encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. PF-4is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum. PF4 (Platelet Factor 4) is a Protein Coding gene. Diseases associated with PF4 include Erythromelalgia and Thrombocytopenia. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Akt Signaling.,PF-4

Gene ID: 5196

UniProt: P02776