PDCD1LG2 antibody (AA 31-80)

Catalog No. ABIN7230572

This Rabbit Polyclonal antibody specifically detects PDCD1LG2 in WB, ELISA and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PDCD1LG2 antibody (AA 31-80) (ABIN7230572)

Target: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDCD1LG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PDCD1LG2 Antibody

Binding Specificity: AA 31-80

Purpose: PD-L2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PD-L2

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PD-L2 protein at AA range: 31-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:500-1:200), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PDCD1LG2

Target: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Alternative Name: PD-L2

Background: Rabbit Anti-PD-L2 Polyclonal Antibody,Programmed cell death 1 ligand 2, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, B7-DC, CD antigen CD273,PDCD1LG2 (Programmed Cell Death 1 Ligand 2) is a Protein Coding gene. Diseases associated with PDCD1LG2 include Cysticercosis and Myasthenic Syndrome, Congenital, 14, With Tubular Aggregates. Among its related pathways are T Cell Co-Signaling Pathway: ligand-Receptor Interactions and Translocation of ZAP-70 to Immunological synapse. An important paralog of this gene is CD274. Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).,PD-L2

Molecular Weight: observerd band 30kDa

Gene ID: 80380

UniProt: Q9BQ51