RAB21 antibody (AA 60-140)

Catalog No. ABIN7230882

This Rabbit Polyclonal antibody specifically detects RAB21 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for RAB21 antibody (AA 60-140) (ABIN7230882)

Target: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB21 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RAB21 Antibody

Binding Specificity: AA 60-140

Purpose: RAB21 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RAB21 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RAB21 protein at AA range: 60-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RAB21

Target: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Alternative Name: RAB21

Background: Rabbit Anti-RAB21 Polyclonal Antibody,Ras-related protein Rab-21,RAB21 (RAB21, Member RAS Oncogene Family) belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of RAB21 is associated with a poor prognosis for glioma patients. RAB21 is downregulated by the tumor suppressor miR-200b and miRNA-200b is itself downregulated in glioma tissues.,RAB21

Molecular Weight: observerd band 24kDa

Gene ID: 23011

UniProt: Q9UL25