RPH3A antibody (pSer237)
Quick Overview for RPH3A antibody (pSer237) (ABIN7220570)
Target
See all RPH3A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- pSer237
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Purpose
- Rabphilin-3A (phospho Ser237) Polyclonal Antibody
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Specificity
- Phospho-Rabphilin-3A (S237) Polyclonal Antibody detects endogenous levels of Rabphilin-3A protein only when phosphorylated at S237.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from human Rabphilin-3A Phospho-Ser237
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RPH3A (Rabphilin 3A (RPH3A))
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Alternative Name
- Rabphilin-3A
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Background
- Rabbit Anti-Rabphilin-3A (phospho Ser237) Polyclonal Antibody,RPH3A, KIAA0985, Rabphilin-3A, Exophilin-1,Exocytosis of neurotransmitters and hormones is fundamental to synaptic neurotransmission and cell-cell communication. RAB3A (MIM 179390) is a small G protein that is thought to act at late stages of exocytosis, and RPH3A is a RAB3A effector (Lin et al. 2007 [PubMed 17149709]).,Rabphilin-3A
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Molecular Weight
- observerd band 75kDa
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Gene ID
- 22895
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UniProt
- Q9Y2J0
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Pathways
- Synaptic Vesicle Exocytosis
Target
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