S100A12 antibody (AA 290-370)

Catalog No. ABIN7229764

The Rabbit Polyclonal anti-S100A12 antibody has been validated for WB and ELISA. It is suitable to detect S100A12 in samples from Human, Mouse and Rat.

Quick Overview for S100A12 antibody (AA 290-370) (ABIN7229764)

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This S100A12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-S100A12 Antibody

Binding Specificity: AA 290-370

Purpose: MRP6 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MRP6 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human MRP6 protein at AA range: 290-370

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for S100A12

Target: S100A12 (S100 Calcium Binding Protein A12 (S100A12))

Alternative Name: MRP6

Background: Rabbit Anti-MRP6 Polyclonal Antibody,Multidrug resistance-associated protein 6, ATP-binding cassette sub-family C member 6, Anthracycline resistance-associated protein, Multi-specific organic anion transporter E, MOAT-E,ABCC6 (ATP Binding Cassette Subfamily C Member 6) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling. The protein encoded by ABCC6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in ABCC6 cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for ABCC6.,MRP6

Molecular Weight: observerd band 165kDa

Gene ID: 368

UniProt: O95255

Pathways: Toll-Like Receptors Cascades, S100 Proteins