PTK6 antibody (AA 201-300) (HRP)

Catalog No. ABIN716615

The Rabbit Polyclonal anti-PTK6 antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect PTK6 in samples from Human and Mouse.

Quick Overview for PTK6 antibody (AA 201-300) (HRP) (ABIN716615)

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTK6 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-PTK6 Antibody (HRP)

Binding Specificity: AA 201-300

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Brk/PTK6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PTK6

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Alternative Name: PTK6

Background:

Synonyms: Breast tumor kinase, Breast tumour kinase, Protein tyrosine kinase 6, PTK6, Tyrosine protein kinase BRK, PTK6_HUMAN.

Background: This protein encoded is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. Its presence in the nucleus appears to be linked to suppression of tumor progression. The encoded protein has been shown to undergo autophosphorylation.

Gene ID: 5753