SNAIL antibody (pSer246)

Catalog No. ABIN7224410

This Rabbit Polyclonal antibody specifically detects SNAIL in WB, ELISA, IF and IHC (p). It exhibits reactivity toward Human, Mouse and Monkey.

Quick Overview for SNAIL antibody (pSer246) (ABIN7224410)

Target: SNAIL (SNAI1)

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAIL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SNAIL Antibody

Binding Specificity: pSer246

Purpose: SNAI 1 (phospho Ser246) Polyclonal Antibody

Specificity: Phospho-SNAI 1 (S246) Polyclonal Antibody detects endogenous levels of SNAI 1 protein only when phosphorylated at S246.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human SNAI 1 Phospho-Ser246

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SNAIL

Target: SNAIL (SNAI1)

Alternative Name: SNAI 1

Background: Rabbit Anti-SNAI 1 (phospho Ser246) Polyclonal Antibody,SNAI1, SNAH, Zinc finger protein SNAI1, Protein snail homolog 1, Protein sna,The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by SNAI1 (snail family transcriptional repressor 1) is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.,Zinc finger protein SNAI1

Molecular Weight: observerd band 29kDa

Gene ID: 6615

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling