Splicing Factor 1 antibody

Catalog No. ABIN7220846

This anti-Splicing Factor 1 antibody is a Rabbit Polyclonal antibody detecting Splicing Factor 1 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Splicing Factor 1 antibody (ABIN7220846)

Target: Splicing Factor 1 (SF1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Splicing Factor 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Splicing Factor 1 Antibody

Purpose: SF-1 Polyclonal Antibody

Specificity: SF-1 Polyclonal Antibody detects endogenous levels of SF-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human SF-1 around the non-phosphorylation site of S203

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Splicing Factor 1

Target: Splicing Factor 1 (SF1)

Alternative Name: SF-1

Background: Rabbit Anti-SF-1 Polyclonal Antibody,NR5A1, AD4BP, FTZF1, SF1, Steroidogenic factor 1, SF-1, STF-1, Adrenal 4-binding protein, Fushi tarazu factor homolog 1, Nuclear receptor subfamily 5 group A member 1, Steroid hormone receptor Ad4BP,The nuclear receptor subfamily 5 group A member 1 encoded by NR5A1 is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect.,Steroidogenic factor 1

Molecular Weight: observerd band 50kDa

Gene ID: 2516

UniProt: Q13285

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Maintenance of Protein Location