SENP3 antibody (AA 10-90)

Catalog No. ABIN7220968

This Rabbit Polyclonal antibody specifically detects SENP3 in WB, ELISA and IHC (p). It exhibits reactivity toward Human and Mouse.

Quick Overview for SENP3 antibody (AA 10-90) (ABIN7220968)

Target: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SENP3 Antibody

Binding Specificity: AA 10-90

Purpose: SENP3 Polyclonal Antibody

Specificity: SENP3 Polyclonal Antibody detects endogenous levels of SENP3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human SENP3 at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SENP3

Target: SENP3 (SUMO/sentrin Specific Peptidase 3 (SENP3))

Alternative Name: SENP3

Background: Rabbit Anti-SENP3 Polyclonal Antibody,SENP3, SSP3, SUSP3, Sentrin-specific protease 3, SUMO-1-specific protease 3, Sentrin/SUMO-specific protease SENP3,The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1, MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al. 2006 [PubMed 16738315]).,Sentrin-specific protease 3

Molecular Weight: observerd band 80kDa

Gene ID: 26168

UniProt: Q9H4L4