TSH receptor antibody (AA 280-360)

Catalog No. ABIN7231944

This anti-TSH receptor antibody is a Rabbit Polyclonal antibody detecting TSH receptor in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for TSH receptor antibody (AA 280-360) (ABIN7231944)

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSH receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TSH receptor Antibody

Binding Specificity: AA 280-360

Purpose: TSHR Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TSHR protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human TSHR protein at AA range: 280-360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for TSH receptor

Target: TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))

Alternative Name: TSHR

Background: Rabbit Anti-TSHR Polyclonal Antibody,Thyrotropin receptor, Thyroid-stimulating hormone receptor, TSH-R,Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin (PubMed: 11847099, PubMed: 12045258). Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2: GPHB5) or thyrostimulin (PubMed: 12045258). The activity of this receptor is mediated by G proteins which activate adenylate cyclase (PubMed: 11847099). Plays a central role in controlling thyroid cell metabolism (By similarity).,TSHR

Molecular Weight: observerd band 84kDa

Gene ID: 7253

UniProt: P16473

Pathways: Thyroid Hormone Synthesis