Nlgn4l antibody (C-Term)

Catalog No. ABIN7233051

This anti-Nlgn4l antibody is a Mouse Monoclonal antibody detecting Nlgn4l in IHC, WB and IF/ICC. Suitable for Mouse.

Quick Overview for Nlgn4l antibody (C-Term) (ABIN7233051)

Target: Nlgn4l (NLGN4L) (Neuroligin 4-Like (NLGN4L))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Nlgn4l antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)

Clone: S98-7

Product Details anti-Nlgn4l Antibody

Binding Specificity: AA 782-945, C-Term

Purpose: Anti-Neuroligin-4 Mouse Monoclonal Antibody

Specificity: This antibody recognizes mouse Neuroligin-4. It does not cross-react with other Neuroligins.

Cross-Reactivity: Mouse, Rat

Immunogen: Fusion protein corresponding to aa 782-945 (intracellular C-terminus) of mouse Neuroligin-4.

Isotype: IgG1

Application Details

Application Notes: Immunoblotting: use at 1-2 μg/mL. A band of ~125-130 kDa is detected.
Immunofluorescence: use at 10 μg/mL.
These are recommended concentrations.
Enduser should determine optimal concentrations for their application.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Dilute in PBS or medium that is identical to that used in the assay system.

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, 0.1 % sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: This product is stable for at least one (1) year at -20°C.

Target Details for Nlgn4l

Target: Nlgn4l (NLGN4L) (Neuroligin 4-Like (NLGN4L))

Alternative Name: Nlgn4l

Background: Neuroligin 4-like,Cell surface protein involved in cell-cell-interactions. Plays a role in the formation or maintenance of synaptic junctions via its interactions (via the extracellular domains) with neurexin family members. Plays a role in synaptic signal transmission. {PubMed:18434543, PubMed:21282647}.,Neuroligin-4 is a neuronal cell surface protein and a member of the type-B carboxylesterase- lipase protein family. Members of this family may act as splice site-specific ligands for beta- neurexins and may be involved in the formation and remodeling of central nervous system synapses. Neuroligin-4 interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants.,Cell membrane, Single-pass type I membrane protein. Cell junction, synapse, postsynaptic cell membrane. Note=Detected at glycinergic postsynapses in retina. Detected on dendritic spines on cultured neurons.,Neuroligin-4, NL-4

UniProt: B0F2B4