ACADSB antibody (AA 133-432)

Catalog No. ABIN7265420

The Rabbit Polyclonal anti-ACADSB antibody has been validated for IHC. It is suitable to detect ACADSB in samples from Human.

Quick Overview for ACADSB antibody (AA 133-432) (ABIN7265420)

Target: ACADSB (Acyl-CoA Dehydrogenase, Short/branched Chain (ACADSB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACADSB antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-ACADSB Antibody

Binding Specificity: AA 133-432

Purpose: ACADSB Rabbit pAb

Sequence: ASVAVFCEIQ NTLINTLIRK HGTEEQKATY LPQLTTEKVG SFCLSEAGAG SDSFALKTRA DKEGDYYVLN GSKMWISSAE HAGLFLVMAN VDPTIGYKGI TSFLVDRDTP GLHIGKPENK LGLRASSTCP LTFENVKVPE ANILGQIGHG YKYAIGSLNE GRIGIAAQML GLAQGCFDYT IPYIKERIQF GKRLFDFQGL QHQVAHVATQ LEAARLLTYN AARLLEAGKP FIKEASMAKY YASEIAGQTT SKCIEWMGGV GYTKDYPVEK YFRDAKIGTI YEGASNIQLN TIAKHIDAEY

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 133-432 of human ACADSB (NP_001600.1).

Isotype: IgG

Application Details

Application Notes: IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ACADSB

Target: ACADSB (Acyl-CoA Dehydrogenase, Short/branched Chain (ACADSB))

Alternative Name: ACADSB

Background: Short/branched chain acyl-CoA dehydrogenase(ACADSB) is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. Substrate specificity is the primary characteristic used to define members of this gene family. The ACADSB gene product has the greatest activity towards the short branched chain acyl-CoA derivative, (S)-2-methylbutyryl-CoA, but also reacts significantly with other 2-methyl branched chain substrates and with short straight chain acyl-CoAs. The cDNA encodes for a mitochondrial precursor protein which is cleaved upon mitochondrial import and predicted to yield a mature peptide of approximately 43.7-KDa.,ACADSB,2-MEBCAD,ACAD7,SBCAD,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Amino acid metabolism,Lipid Metabolism,Cardiovascular,Lipids,Fatty Acids,ACADSB

Molecular Weight: 36kDa/47kDa

Gene ID: 36

UniProt: P45954

Pathways: Monocarboxylic Acid Catabolic Process