ASB2 antibody (AA 448-587)

Catalog No. ABIN7265612

The Rabbit Polyclonal anti-ASB2 antibody has been validated for WB. It is suitable to detect ASB2 in samples from Human.

Quick Overview for ASB2 antibody (AA 448-587) (ABIN7265612)

Target: ASB2 (Ankyrin Repeat and SOCS Box-Containing 2 (ASB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ASB2 Antibody

Binding Specificity: AA 448-587

Purpose: ASB2 Rabbit pAb

Sequence: MDLGCDGEPC FSCLYGNGPH PPAPQPSSRF NDAPAADKEP SVVQFCEFVS APEVSRWAGP IIDVLLDYVG NVQLCSRLKE HIDSFEDWAV IKEKAEPPRP LAHLCRLRVR KAIGKYRIKL LDTLPLPGRL IRYLKYENTQ

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 448-587 of human ASB2 (NP_057234.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ASB2

Target: ASB2 (Ankyrin Repeat and SOCS Box-Containing 2 (ASB2))

Alternative Name: ASB2

Background: This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,ASB-2,ASB2,ASB2

Molecular Weight: 65kDa

Gene ID: 51676

UniProt: Q96Q27