BOK antibody (AA 1-100)

Catalog No. ABIN7265866

This Rabbit Polyclonal antibody specifically detects BOK in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for BOK antibody (AA 1-100) (ABIN7265866)

Target: BOK (BCL2-Related Ovarian Killer (BOK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BOK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-BOK Antibody

Binding Specificity: AA 1-100

Purpose: BOK Rabbit pAb

Sequence: MEVLRRSSVF AAEIMDAFDR SPTDKELVAQ AKALGREYVH ARLLRAGLSW SAPERAAPVP GRLAEVCAVL LRLGDELEMI RPSVYRNVAR QLHISLQSEP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BOK (NP_115904.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BOK

Target: BOK (BCL2-Related Ovarian Killer (BOK))

Alternative Name: BOK

Background: The protein encoded by this gene belongs to the BCL2 family, members of which form homo- or heterodimers, and act as anti- or proapoptotic regulators that are involved in a wide variety of cellular processes. Studies in rat show that this protein has restricted expression in reproductive tissues, interacts strongly with some antiapoptotic BCL2 proteins, not at all with proapoptotic BCL2 proteins, and induces apoptosis in transfected cells. Thus, this protein represents a proapoptotic member of the BCL2 family.,BOK,BCL2L9,BOKL,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Apoptosis,BOK

Molecular Weight: 14kDa/23kDa

Gene ID: 666

UniProt: Q9UMX3

Pathways: Positive Regulation of Endopeptidase Activity