BNIP3 antibody (AA 1-140)

Catalog No. ABIN7265869

This Rabbit Polyclonal antibody specifically detects BNIP3 in IF. It exhibits reactivity toward Human.

Quick Overview for BNIP3 antibody (AA 1-140) (ABIN7265869)

Target: BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BNIP3 antibody is un-conjugated

Application: Immunofluorescence (IF)

Product Details anti-BNIP3 Antibody

Binding Specificity: AA 1-140

Purpose: BNIP3 Rabbit pAb

Sequence: MGDAAADPPG PALPCEFLRP GCGAPLSPGA QLGRGAPTSA FPPPAAEAHP AARRGLRSPQ LPSGAMSQNG APGMQEESLQ GSWVELHFSN NGNGGSVPAS VSIYNGDMEK ILLDAQHESG RSSSKSSHCD SPPRSQTPQD

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human BNIP3 (NP_004043.3).

Isotype: IgG

Application Details

Application Notes: IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BNIP3

Target: BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

Alternative Name: BNIP3

Background: This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation.,BNIP3,NIP3,Cancer,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Cardiovascular,Hypoxia,Heart,Mitochondrial Control of Autophagy,BNIP3

Molecular Weight: 27kDa

Gene ID: 664

UniProt: Q12983

Pathways: Autophagy, Brown Fat Cell Differentiation