BLOC1S3 antibody (AA 1-202)

Catalog No. ABIN7265884

Product Details anti-BLOC1S3 Antibody

Target: BLOC1S3 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))

Binding Specificity: AA 1-202

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BLOC1S3 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Purpose: BLOC1S3 Rabbit pAb

Sequence: MASQGRRRRP LRRPETVVPG EATETDSERS ASSSEEEELY LGPSGPTRGR PTGLRVAGEA AETDSEPEPE PEPTAAPRDL PPLVVQRESA EEAWGTEEAP APAPARSLLQ LRLAESQARL DHDVAAAVSG VYRRAGRDVA ALASRLAAAQ AAGLAAAHSV RLARGDLCAL AERLDIVAGC RLLPDIRGVP GTEPEKDPGP RA

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-202 of human BLOC1S3 (NP_997715.1).

Isotype: IgG

Application Details

Application Notes: IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BLOC1S3

Target: BLOC1S3 (Biogenesis of Lysosomal Organelles Complex-1, Subunit 3 (BLOC1S3))

Alternative Name: BLOC1S3 (BLOC1S3 Products)

Background: This gene encodes a protein that is a component of the BLOC1 multi-subunit protein complex. This complex is necessary for the biogenesis of specialized organelles of the endosomal-lysosomal system, including platelet dense granules and melanosomes. Mutations in this gene cause Hermansky-Pudlak syndrome 8, a disease characterized by lysosomal storage defects, bleeding due to platelet storage pool deficiency, and oculocutaneous albinism.,BLOC1S3,BLOS3,HPS8,RP,Signal Transduction,BLOC1S3

Gene ID: 388552

UniProt: Q6QNY0