BOLA3 antibody (AA 1-68)

Catalog No. ABIN7265891

The Rabbit Polyclonal anti-BOLA3 antibody has been validated for IHC and WB. It is suitable to detect BOLA3 in samples from Human.

Quick Overview for BOLA3 antibody (AA 1-68) (ABIN7265891)

Target: BOLA3 (BolA Homolog 3 (BOLA3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BOLA3 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Product Details anti-BOLA3 Antibody

Binding Specificity: AA 1-68

Purpose: BOLA3 Rabbit pAb

Sequence: MAAWSPAAAA PLLRGIRGLP LHHRMFATQT EGELRVTQIL KEKFPRATAI KVTDISGGCG AMYEIKIE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-68 of human BOLA3 (NP_997717.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for BOLA3

Target: BOLA3 (BolA Homolog 3 (BOLA3))

Alternative Name: BOLA3

Background: This gene encodes a protein that plays an essential role in the production of iron-sulfur (Fe-S) clusters for the normal maturation of lipoate-containing 2-oxoacid dehydrogenases, and for the assembly of the mitochondrial respiratory chain complexes. Mutation in this gene has been associated with multiple mitochondrial dysfunctions syndrome-2. Two alternatively spliced transcript variants encoding different isoforms with distinct subcellular localization have been reported for this gene (PMID:21944046).,BOLA3,MMDS2,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Oxidative phosphorylation,BOLA3

Molecular Weight: 11kDa/12kDa

Gene ID: 388962

UniProt: Q53S33