Cadherin 13 antibody

Catalog No. ABIN7265996

The Rabbit Monoclonal anti-Cadherin 13 antibody has been validated for WB and IHC. It is suitable to detect Cadherin 13 in samples from Human.

Quick Overview for Cadherin 13 antibody (ABIN7265996)

Target: Cadherin 13 (CDH13)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Cadherin 13 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Cadherin 13 Antibody

Purpose: Cadherin-13 (CDH13) Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Cadherin-13 (CDH13)

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cadherin 13

Target: Cadherin 13 (CDH13)

Alternative Name: CDH13

Background: This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011],CDHH, P105,Calcium Signaling,Cancer,Cell Adhesion,Cell Adhesion_Cadherins,Cell Biology & Developmental Biology,Cell Cycle,Cell Cycle_Centrosome,Cytoskeleton,Invasion and Metastasis,Neuroscience,Signal Transduction,CDH13

Molecular Weight: 105,130kDa

Gene ID: 1012

UniProt: P55290

Pathways: EGFR Signaling Pathway, Cell-Cell Junction Organization