Calpain 7 antibody (AA 20-220)

Catalog No. ABIN7266034

This Rabbit Polyclonal antibody specifically detects Calpain 7 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for Calpain 7 antibody (AA 20-220) (ABIN7266034)

Target: Calpain 7 (CAPN7)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Calpain 7 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Calpain 7 Antibody

Binding Specificity: AA 20-220

Purpose: CAPN7 Rabbit pAb

Sequence: RDHEGRYSEA VFYYKEAAQA LIYAEMAGSS LENIQEKITE YLERVQALHS AVQSKSADPL KSKHQLDLER AHFLVTQAFD EDEKENVEDA IELYTEAVDL CLKTSYETAD KVLQNKLKQL ARQALDRAEA LSEPLTKPVG KISSTSVKPK PPPVRAHFPL GANPFLERPQ SFISPQSCDA QGQRYTAEEI EVLRTTSKIN G

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-220 of human CAPN7 (NP_055111.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Calpain 7

Target: Calpain 7 (CAPN7)

Alternative Name: CAPN7

Background: Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The function of the protein encoded by this gene is not known. An orthologue has been found in mouse but it seems to diverge from other family members. The mouse orthologue is thought to be calcium independent with protease activity. [provided by RefSeq, Jul 2008],CALPAIN7,PALBH,CAPN7,calpain-7,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Calcium Signaling,CAPN7

Molecular Weight: 92kDa

Gene ID: 23473

UniProt: Q9Y6W3