CD68 antibody (AA 16-200)

Catalog No. ABIN7266212

The Rabbit Polyclonal anti-CD68 antibody has been validated for WB, IF and IHC. It is suitable to detect CD68 in samples from Human.

Quick Overview for CD68 antibody (AA 16-200) (ABIN7266212)

Target: CD68 (CD68 Molecule (CD68))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD68 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-CD68 Antibody

Binding Specificity: AA 16-200

Purpose: CD68 Rabbit pAb

Sequence: AAQGTGNDCP HKKSATLLPS FTVTPTVTES TGTTSHRTTK SHKTTTHRTT TTGTTSHGPT TATHNPTTTS HGNVTVHPTS NSTATSQGPS TATHSPATTS HGNATVHPTS NSTATSPGFT SSAHPEPPPP SPSPSPTSKE TIGDYTWTNG SQPCVHLQAQ IQIRVMYTTQ GGGEAWGISV LNPNK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 16-200 of human CD68 (NP_001242.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CD68

Target: CD68 (CD68 Molecule (CD68))

Alternative Name: CD68

Background: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.,CD68,GP110,LAMP4,SCARD1,Immunology & Inflammation,CD markers,CD68

Molecular Weight: 31kDa/34kDa/37kDa

Gene ID: 968

UniProt: P34810