CCDC50 antibody (AA 10-147)

Catalog No. ABIN7266439

This Rabbit Polyclonal antibody specifically detects CCDC50 in WB. It exhibits reactivity toward Human.

Quick Overview for CCDC50 antibody (AA 10-147) (ABIN7266439)

Target: CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC50 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCDC50 Antibody

Binding Specificity: AA 10-147

Purpose: CCDC50 Rabbit pAb

Sequence: KLPGVKEVCR DFAVLEDHTL AHSLQEQEIE HHLASNVQRN RLVQHDLQVA KQLQEEDLKA QAQLQKRYKD LEQQDCEIAQ EIQEKLAIEA ERRRIQEKKD EDIARLLQEK ELQEEKKRKK HFPEFPATRA YADSYYYE

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 10-147 of human CCDC50 (NP_777568.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CCDC50

Target: CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))

Alternative Name: CCDC50

Background: This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008],C3orf6,DFNA44,YMER,CCDC50,Epigenetics & Nuclear Signaling,Transcription Factors,CCDC50

Molecular Weight: 35kDa/56kDa

Gene ID: 152137

UniProt: Q8IVM0