Coilin antibody
Quick Overview for Coilin antibody (ABIN7266451)
Target
See all Coilin (COIL) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- Coilin Rabbit mAb
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Cross-Reactivity
- Human, Mouse
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- A synthesized peptide derived from human Coilin
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Coilin (COIL)
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Alternative Name
- COIL
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Background
- The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. [provided by RefSeq, Jul 2008],CLN80, p80-coilin,Cell Type Marker,Cell Type Marker_Neuron marker,Epigenetics & Nuclear Signaling,Neuroscience,COIL
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Molecular Weight
- 80kDa
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Gene ID
- 8161
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UniProt
- P38432
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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