COX11 antibody (AA 140-240)

Catalog No. ABIN7266513

This anti-COX11 antibody is a Rabbit Polyclonal antibody detecting COX11 in WB. Suitable for Human.

Quick Overview for COX11 antibody (AA 140-240) (ABIN7266513)

Target: COX11 (COX11 Cytochrome C Oxidase Assembly (COX11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX11 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COX11 Antibody

Binding Specificity: AA 140-240

Purpose: COX11 Rabbit pAb

Sequence: ENMVPVKDRI IKISFNADVH ASLQWNFRPQ QTEIYVVPGE TALAFYRAKN PTDKPVIGIS TYNIVPFEAG QYFNKIQCFC FEEQRLNPQE EVDMPVFFYI D

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human COX11 (NP_004366.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COX11

Target: COX11 (COX11 Cytochrome C Oxidase Assembly (COX11))

Alternative Name: COX11

Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to contain a transmembrane domain localized in the mitochondrial inner membrane. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene has been found on chromosome 6.,COX11,COX11P,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,COX11

Molecular Weight: 26kDa/31kDa

Gene ID: 1353

UniProt: Q9Y6N1

Pathways: Regulation of Carbohydrate Metabolic Process