CHORDC1 antibody (AA 60-160)

Catalog No. ABIN7266619

This Rabbit Polyclonal antibody specifically detects CHORDC1 in WB. It exhibits reactivity toward Human.

Quick Overview for CHORDC1 antibody (AA 60-160) (ABIN7266619)

Target: CHORDC1 (Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHORDC1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHORDC1 Antibody

Binding Specificity: AA 60-160

Purpose: CHORDC1 Rabbit pAb

Sequence: TKGRHNSEKP PEPVKPEVKT TEKKELCELK PKFQEHIIQA PKPVEAIKRP SPDEPMTNLE LKISASLKQA LDKLKLSSGN EENKKEEDND EIKIGTSCKN G

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-160 of human CHORDC1 (NP_036256.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CHORDC1

Target: CHORDC1 (Cysteine and Histidine-Rich Domain (CHORD)-Containing 1 (CHORDC1))

Alternative Name: CHORDC1

Background: Regulates centrosome duplication, probably by inhibiting the kinase activity of ROCK2. Proposed to act as co-chaperone for HSP90. May play a role in the regulation of NOD1 via a HSP90 chaperone complex. In vitro, has intrinsic chaperone activity. This function may be achieved by inhibiting association of ROCK2 with NPM1. Plays a role in ensuring the localization of the tyrosine kinase receptor EGFR to the plasma membrane, and thus ensures the subsequent regulation of EGFR activity and EGF-induced actin cytoskeleton remodeling. Involved in stress response. Prevents tumorigenesis.,CHORDC1,CHP1,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,CHORDC1

Gene ID: 26973

UniProt: Q9UHD1