COX6C antibody (AA 1-75)

Catalog No. ABIN7266643

This Rabbit Polyclonal antibody specifically detects COX6C in WB and IF. It exhibits reactivity toward Human.

Quick Overview for COX6C antibody (AA 1-75) (ABIN7266643)

Target: COX6C (Cytochrome C Oxidase Subunit VIc (COX6C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX6C antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-COX6C Antibody

Binding Specificity: AA 1-75

Purpose: COX6C Rabbit pAb

Sequence: MAPEVLPKPR MRGLLARRLR NHMAVAFVLS LGVAALYKFR VADQRKKAYA DFYRNYDVMK DFEEMRKAGI FQSVK

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-75 of human COX6C (NP_004365.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COX6C

Target: COX6C (Cytochrome C Oxidase Subunit VIc (COX6C))

Alternative Name: COX6C

Background: Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77 % amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12.,COX6C,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Mitochondrial markers,Oxidative phosphorylation,Neuroscience,Neurodegenerative Diseases,COX6C

Molecular Weight: 8kDa

Gene ID: 1345

UniProt: P09669

Pathways: Proton Transport