Cytohesin 1 antibody (AA 1-70)

Catalog No. ABIN7266661

This Rabbit Polyclonal antibody specifically detects Cytohesin 1 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for Cytohesin 1 antibody (AA 1-70) (ABIN7266661)

Target: Cytohesin 1 (CYTH1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cytohesin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Cytohesin 1 Antibody

Binding Specificity: AA 1-70

Purpose: CYTH1 Rabbit pAb

Sequence: MEEDDSYVPS DLTAEERQEL ENIRRRKQEL LADIQRLKDE IAEVANEIEN LGSTEERKNM QRNKQVAMGR

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human CYTH1 (NP_004753.1).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Cytohesin 1

Target: Cytohesin 1 (CYTH1)

Alternative Name: CYTH1

Background: The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes. A pseudogene of this gene has been defined on the X chromosome. Alternative splicing results in multiple transcript variants.,CYTH1,B2-1,CYTOHESIN-1,D17S811E,PSCD1,SEC7,Signal Transduction,CYTH1

Molecular Weight: 39kDa/46kDa

Gene ID: 9267

UniProt: Q15438