DOCK4 antibody (AA 150-450)

Catalog No. ABIN7266717

This anti-DOCK4 antibody is a Rabbit Polyclonal antibody detecting DOCK4 in WB. Suitable for Human.

Quick Overview for DOCK4 antibody (AA 150-450) (ABIN7266717)

Target: DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DOCK4 Antibody

Binding Specificity: AA 150-450

Purpose: DOCK4 Rabbit pAb

Sequence: LDWGNEQLGL DLVPRKEYAM VDPEDISITE LYRLMEHRHR KKDTPVQASS HHLFVQMKSL MCSNLGEELE VIFSLFDSKE NRPISERFFL RLNRNGLPKA PDKPERHCSL FVDLGSSELR KDIYITVHII RIGRMGAGEK KNACSVQYRR PFGCAVLSIA DLLTGETKDD LILKVYMCNT ESEWYQIHEN IIKKLNARYN LTGSNAGLAV SLQLLHGDIE QIRREYSSVF SHGVSITRKL GFSNIIMPGE MRNDLYITIE RGEFEKGGKS VARNVEVTMF IVDSSGQTLK DFISFGSGEP P

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 150-450 of human DOCK4 (NP_055520.3).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DOCK4

Target: DOCK4 (Dedicator of Cytokinesis 4 (DOCK4))

Alternative Name: DOCK4

Background: This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain, a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated, cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian, prostate, glioma, and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described, but only one has been fully characterized.,DOCK4,Signal Transduction,G protein signaling,Signal Transduction,DOCK4

Molecular Weight: 29kDa/222kDa/225kDa/226kDa

Gene ID: 9732

UniProt: Q8N1I0