Desmoglein 2 antibody

Catalog No. ABIN7266740

The Rabbit Monoclonal anti-Desmoglein 2 antibody has been validated for WB. It is suitable to detect Desmoglein 2 in samples from Human.

Quick Overview for Desmoglein 2 antibody (ABIN7266740)

Target: Desmoglein 2 (DSG2)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Desmoglein 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Desmoglein 2 Antibody

Purpose: Desmoglein 2 Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Desmoglein 2

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Desmoglein 2

Target: Desmoglein 2 (DSG2)

Alternative Name: DSG2

Background: This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016],CDHF5, HDGC,Cancer,Cardiovascular,Cell Adhesion,Cell Adhesion_Cadherins,Cell Biology & Developmental Biology,Cytoskeleton,Heart,Heart_Cardiac arrhythmias,Invasion and Metastasis,Signal Transduction,DSG2

Molecular Weight: 160kDa

Gene ID: 1829

UniProt: Q14126

Pathways: Cell-Cell Junction Organization