DPYSL2 antibody (AA 400-500)

Catalog No. ABIN7266769

This Rabbit Polyclonal antibody specifically detects DPYSL2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for DPYSL2 antibody (AA 400-500) (ABIN7266769)

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPYSL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Grade: KO Validated

Product Details anti-DPYSL2 Antibody

Binding Specificity: AA 400-500

Purpose: [KO Validated] CRMP2/DPYSL2 Rabbit pAb

Sequence: RIAVGSDADL VIWDPDSVKT ISAKTHNSSL EYNIFEGMEC RGSPLVVISQ GKIVLEDGTL HVTEGSGRYI PRKPFPDFVY KRIKARSRLA ELRGVPRGLY D

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 400-500 of human CRMP2/CRMP2/DPYSL2 (NP_001377.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DPYSL2

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Alternative Name: DPYSL2

Background: This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,DPYSL2,CRMP-2,CRMP2,DHPRP2,DRP-2,DRP2,N2A3,ULIP-2,ULIP2,Cell Biology & Developmental Biology,Microtubules,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,DPYSL2

Molecular Weight: 58kDa/62kDa

Gene ID: 1808

UniProt: Q16555

Pathways: Regulation of Cell Size