DMAP1 antibody
Quick Overview for DMAP1 antibody (ABIN7266814)
Target
See all DMAP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purpose
- DMAP1 Rabbit mAb
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Monoclonal Antibodies
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Purification
- Affinity purification
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Immunogen
- Recombinant protein of human DMAP1.
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Isotype
- IgG
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Application Notes
- WB,1:500 - 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
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Alternative Name
- DMAP1
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Background
- This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.,DMAP1, DNMAP1, DNMTAP1, EAF2, MEAF2, SWC4, DNA methyltransferase 1-associated protein 1,Epigenetics & Nuclear Signaling,DMAP1
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Molecular Weight
- 53kDa
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Gene ID
- 55929
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UniProt
- Q9NPF5
Target
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