DRAM antibody (AA 100-200)

Catalog No. ABIN7266817

This Rabbit Polyclonal antibody specifically detects DRAM in WB. It exhibits reactivity toward Human.

Quick Overview for DRAM antibody (AA 100-200) (ABIN7266817)

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRAM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DRAM Antibody

Binding Specificity: AA 100-200

Purpose: DRAM1 Rabbit pAb

Sequence: GLVGCFGMGI VANFQELAVP VVHDGGALLA FVCGVVYTLL QSIISYKSCP QWNSLSTCHI RMVISAVSCA AVIPMIVCAS LISITKLEWN PREKDYVYHV V

Cross-Reactivity: Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human DRAM1 (NP_060840.2).

Isotype: IgG

Application Details

Application Notes: WB,1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for DRAM

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Alternative Name: DRAM1

Background: This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.,DRAM1,DRAM,Cancer,Tumor suppressors,p53 pathway,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,Cardiovascular,Heart,DRAM1

Molecular Weight: 13kDa/26kDa

Gene ID: 55332

UniProt: Q8N682