FBXO8 antibody (AA 110-250)

Catalog No. ABIN7267096

This Rabbit Polyclonal antibody specifically detects FBXO8 in WB. It exhibits reactivity toward Human.

Quick Overview for FBXO8 antibody (AA 110-250) (ABIN7267096)

Target: FBXO8 (F-Box Protein 8 (FBXO8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXO8 Antibody

Binding Specificity: AA 110-250

Purpose: FBXO8 Rabbit pAb

Sequence: GLCKSTWGHC SIYNKNPPLG FSFRKLYMQL DEGSLTFNAN PDEGVNYFMS KGILDDSPKE IAKFIFCTRT LNWKKLRIYL DERRDVLDDL VTLHNFRNQF LPNALREFFR HIHAPEERGE YLETLITKFS HRFCACNPDL M

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 110-250 of human FBXO8 (NP_036312.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FBXO8

Target: FBXO8 (F-Box Protein 8 (FBXO8))

Alternative Name: FBXO8

Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008],DC10,FBS,FBX8,FBXO8,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Ubiquitin,FBXO8

Molecular Weight: 32kDa/37kDa

Gene ID: 26269

UniProt: Q9NRD0