FAM107A antibody (AA 1-144)

Catalog No. ABIN7267100

The Rabbit Polyclonal anti-FAM107A antibody has been validated for WB. It is suitable to detect FAM107A in samples from Human.

Quick Overview for FAM107A antibody (AA 1-144) (ABIN7267100)

Target: FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM107A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FAM107A Antibody

Binding Specificity: AA 1-144

Purpose: FAM107A Rabbit pAb

Sequence: MYSEIQRERA DIGGLMARPE YREWNPELIK PKKLLNPVKA SRSHQELHRE LLMNHRRGLG VDSKPELQRV LEHRRRNQLI KKKKEELEAK RLQCPFEQEL LRRQQRLNQL EKPPEKEEDH APEFIKVREN LRRIATLTSE EREL

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-144 of human FAM107A (NP_009108.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FAM107A

Target: FAM107A (Family with Sequence Similarity 107, Member A (FAM107A))

Alternative Name: FAM107A

Background: Stress-inducible actin-binding protein that plays a role in synaptic and cognitive functions by modulating actin filamentous (F-actin dynamics. Mediates polymerization of globular actin to F-actin. Also binds to, stabilizes and bundles F-actin. Involved in synaptic function by regulating neurite outgrowth in an actin-dependent manner and for the acquisition of hippocampus-dependent cognitive function, such as learning and long-term memory (By similarity. Plays a role in the actin and microtubule cytoskeleton organization, negatively regulates focal adhesion (FA assembly promoting malignant glial cell migration in an actin-, microtubule- and MAP1A-dependent manner. Also involved in neuroblastoma G1/S phase cell cycle progression and cell proliferation inhibition by stimulating ubiquitination of NF-kappa-B subunit RELA and NF-kappa-B degradation in a COMMD1- and actin-dependent manner. May play a role in tumor development.,FAM107A,DRR1,TU3A,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,FAM107A

Molecular Weight: 15kDa/17kDa/20kDa

Gene ID: 11170

UniProt: O95990