FCHO2 antibody (AA 1-300)

Catalog No. ABIN7267163

The Rabbit Polyclonal anti-FCHO2 antibody has been validated for WB. It is suitable to detect FCHO2 in samples from Human.

Quick Overview for FCHO2 antibody (AA 1-300) (ABIN7267163)

Target: FCHO2 (FCH Domain Only 2 (FCHO2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FCHO2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FCHO2 Antibody

Binding Specificity: AA 1-300

Purpose: FCHO2 Rabbit pAb

Sequence: MVMAYFVENF WGEKNSGFDV LYHNMKHGQI STKELADFVR ERATIEEAYS RSMTKLAKSA SNYSQLGTFA PVWDVFKTST EKLANCHLDL VRKLQELIKE VQKYGEEQVK SHKKTKEEVA GTLEAVQTIQ SITQALQKSK ENYNAKCVEQ ERLKKEGATQ REIEKAAVKS KKATDTYKLY VEKYALAKAD FEQKMTETAQ KFQDIEETHL IHIKEIIGSL SNAIKEIHLQ IGQVHEEFIN NMANTTVESL IQKFAESKGT GKERPGLIEF EECDTASAVE GIKPRKRKTF ALPGIIKKEK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human FCHO2 (NP_620137.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FCHO2

Target: FCHO2 (FCH Domain Only 2 (FCHO2))

Alternative Name: FCHO2

Background: Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5 biphosphate like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferrin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor.,FCHO2,Cell Biology & Developmental Biology,FCHO2

Molecular Weight: 43kDa/85kDa/88kDa

Gene ID: 115548

UniProt: Q0JRZ9