FLCN antibody (AA 1-130)

Catalog No. ABIN7267226

Product Details anti-FLCN Antibody

Target: FLCN (Folliculin (FLCN))

Binding Specificity: AA 1-130

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLCN antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purpose: FLCN Rabbit pAb

Sequence: MNAIVALCHF CELHGPRTLF CTEVLHAPLP QGDGNEDSPG QGEQAEEEEG GIQMNSRMRA HSPAEGASVE SSSPGPKKSD MCEGCRSLAA GHPGYISHDK ETSIKYVSHQ HPSHPQLFSI VRQACVRSLS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-130 of human FLCN (NP_653207.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FLCN

Target: FLCN (Folliculin (FLCN))

Alternative Name: FLCN (FLCN Products)

Target Type: Amino Acid

Background: This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.,FLCN,BHD,FLCL,Cancer,Tumor suppressors,Signal Transduction,PI3K-Akt Signaling Pathway,Regulator of mTOR complex function,FLCN

Molecular Weight: 20kDa/37kDa/64kDa

Gene ID: 201163

UniProt: Q8NFG4

Pathways: Cell-Cell Junction Organization