GCAT antibody (AA 170-419)

Catalog No. ABIN7267461

This anti-GCAT antibody is a Rabbit Polyclonal antibody detecting GCAT in WB, IHC and IF. Suitable for Human.

Quick Overview for GCAT antibody (AA 170-419) (ABIN7267461)

Target: GCAT (Glycine C-Acetyltransferase (GCAT))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GCAT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GCAT Antibody

Binding Specificity: AA 170-419

Purpose: GCAT Rabbit pAb

Sequence: KAHKYRYRHL DMADLEAKLQ EAQKHRLRLV ATDGAFSMDG DIAPLQEICC LASRYGALVF MDECHATGFL GPTGRGTDEL LGVMDQVTII NSTLGKALGG ASGGYTTGPG PLVSLLRQRA RPYLFSNSLP PAVVGCASKA LDLLMGSNTI VQSMAAKTQR FRSKMEAAGF TISGASHPIC PVMLGDARLA SRMADDMLKR GIFVIGFSYP VVPKGKARIR VQISAVHSEE DIDRCVEAFV EVGRLHGALP

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 170-419 of human GCAT (NP_055106.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for GCAT

Target: GCAT (Glycine C-Acetyltransferase (GCAT))

Alternative Name: GCAT

Background: The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.,GCAT,KBL,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,GCAT

Molecular Weight: 45kDa/47kDa

Gene ID: 23464

UniProt: O75600