HN1 antibody (AA 1-154)

Catalog No. ABIN7267601

The Rabbit Polyclonal anti-HN1 antibody has been validated for WB. It is suitable to detect HN1 in samples from Human.

Quick Overview for HN1 antibody (AA 1-154) (ABIN7267601)

Target: HN1 (Hematological and Neurological Expressed 1 (HN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HN1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HN1 Antibody

Binding Specificity: AA 1-154

Purpose: HN1 Rabbit pAb

Sequence: MTTTTTFKGV DPNSRNSSRV LRPPGGGSNF SLGFDEPTEQ PVRKNKMASN IFGTPEENQA SWAKSAGAKS SGGREDLESS GLQRRNSSEA SSGDFLDLKG EGDIHENVDT DLPGSLGQSE EKPVPAAPVP SPVAPAPVPS RRNPPGGKSS LVLG

Cross-Reactivity: Human

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human HN1 (NP_057269.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for HN1

Target: HN1 (Hematological and Neurological Expressed 1 (HN1))

Alternative Name: HN1

Background: Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation.,JPT1,ARM2,HN1,HN1A,Cell Biology & Developmental Biology,HN1

Molecular Weight: 11kDa/16kDa/19kDa

Gene ID: 51155

UniProt: Q9UK76