Histone 3 antibody (H3R2me)

Catalog No. ABIN7267686

This anti-Histone 3 antibody is a Rabbit Monoclonal antibody detecting Histone 3 in WB and ChIP. Suitable for Human.

Quick Overview for Histone 3 antibody (H3R2me) (ABIN7267686)

Target: Histone 3 (H3) (Histone H3 (H3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Histone 3 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Product Details anti-Histone 3 Antibody

Binding Specificity: H3R2me

Purpose: MonoMethyl-Histone H3-R2 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Methylated Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Histone H3 (mono methyl R2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,ChIP,1:20 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Histone 3

Target: Histone 3 (H3) (Histone H3 (H3))

Alternative Name: Histone H3

Background: This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.,H3/A,H3C2,H3C3,H3C4,H3C6,H3C7,H3C8,H3FA,H3C10,H3C11,H3C12,HIST1H3A,Histone H3

Molecular Weight: 15kDa

Gene ID: 8290, 8350

UniProt: Q16695, P68431