Histone H2A antibody

Catalog No. ABIN7267723

This Rabbit Monoclonal antibody specifically detects Histone H2A in WB. It exhibits reactivity toward Human.

Quick Overview for Histone H2A antibody (ABIN7267723)

Target: Histone H2A

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Histone H2A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Histone H2A Antibody

Purpose: Histone H2A.Z Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Histone H2A.Z

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Histone H2A

Target: Histone H2A

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008],H2A.Z-1, H2A.z, H2A/z, H2AZ,Epigenetics & Nuclear Signaling,Histones,Histone H2A

Molecular Weight: 13kDa

Gene ID: 3015

UniProt: P0C0S5