Histone H4 antibody (pSer1)

Catalog No. ABIN7267753

This Rabbit Polyclonal antibody specifically detects Histone H4 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Histone H4 antibody (pSer1) (ABIN7267753)

Target: Histone H4

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Histone H4 Antibody

Binding Specificity: pSer1

Purpose: Phospho-Histone H4-S1 Rabbit pAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Phosphorylated Antibodies

Purification: Affinity purification

Immunogen: A phospho specific peptide corresponding to residues surrounding S1 of human Histone H4.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Histone H4

Target: Histone H4

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. [provided by RefSeq, Aug 2015],H4FA,Histone H4,HIST1H4A,HIST4H4,H4/p,Cell Biology & Developmental Biology,Cell Cycle,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Phosphorylation,Histone H4

Molecular Weight: 11kDa

Gene ID: 8359

UniProt: P62805