Integrin alpha 1 antibody (AA 700-800)

Catalog No. ABIN7267917

This anti-Integrin alpha 1 antibody is a Rabbit Polyclonal antibody detecting Integrin alpha 1 in WB. Suitable for Human.

Quick Overview for Integrin alpha 1 antibody (AA 700-800) (ABIN7267917)

Target: Integrin alpha 1 (ITGA1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin alpha 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Integrin alpha 1 Antibody

Binding Specificity: AA 700-800

Purpose: ITGA1 Rabbit pAb

Sequence: ATVCFDVKLK SKEDTIYEAD LQYRVTLDSL RQISRSFFSG TQERKVQRNI TVRKSECTKH SFYMLDKHDF QDSVRITLDF NLTDPENGPV LDDSLPNSVH E

Cross-Reactivity: Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 700-800 of human ITGA1 (NP_852478.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Integrin alpha 1

Target: Integrin alpha 1 (ITGA1)

Alternative Name: ITGA1

Background: This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.,ITGA1,CD49a,VLA1,Signal Transduction,PI3K-Akt Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Immunology & Inflammation,CD markers,Stem Cells,Mesenchymal Stem Cells,ITGA1

Molecular Weight: 130kDa

Gene ID: 3672

UniProt: P56199

Pathways: EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex