Integrin beta 4 antibody

Catalog No. ABIN7267931

The Rabbit Monoclonal anti-Integrin beta 4 antibody has been validated for WB. It is suitable to detect Integrin beta 4 in samples from Human.

Quick Overview for Integrin beta 4 antibody (ABIN7267931)

Target: Integrin beta 4 (ITGB4)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Integrin beta 4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Integrin beta 4 Antibody

Purpose: Integrin beta 4 (ITGB4/CD104) Rabbit mAb

Cross-Reactivity: Human, Mouse

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human Integrin beta 4 (ITGB4/CD104) (ITGB4/CD104)

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Integrin beta 4

Target: Integrin beta 4 (ITGB4)

Alternative Name: ITGB4

Background: Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],CD104, GP150,CDs,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,G protein signaling,G protein signaling_G-Protein-Coupled Receptors Signaling to MAPK/Erk,Immunology & Inflammation,MAPK-Erk Signaling Pathway,PI3K-Akt Signaling Pathway,Signal Transduction,ITGB4

Molecular Weight: 210kDa

Gene ID: 3691

UniProt: P16144

Pathways: Integrin Complex