L2HGDH antibody (AA 1-220)

Catalog No. ABIN7268160

This anti-L2HGDH antibody is a Rabbit Polyclonal antibody detecting L2HGDH in WB and IF. Suitable for Human.

Quick Overview for L2HGDH antibody (AA 1-220) (ABIN7268160)

Target: L2HGDH (L-2-Hydroxyglutarate Dehydrogenase (L2HGDH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This L2HGDH antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-L2HGDH Antibody

Binding Specificity: AA 1-220

Purpose: L2HGDH Rabbit pAb

Sequence: MVPALRYLVG ACGRARGLFA GGSPGACGFA SGRPRPLCGG SRSASTSSFD IVIVGGGIVG LASARALILR HPSLSIGVLE KEKDLAVHQT GHNSGVIHSG IYYKPESLKA KLCVQGAALL YEYCQQKGIS YKQCGKLIVA VEQEEIPRLQ ALYEKGLQNG VPGLRLIQQE DIKKKEPYCR GLMAIDCPHT GIVDYRQVAL SFAQDFQEAG GSVLTNFEVK

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human L2HGDH (NP_079160.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for L2HGDH

Target: L2HGDH (L-2-Hydroxyglutarate Dehydrogenase (L2HGDH))

Alternative Name: L2HGDH

Background: This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation.,L2HGDH,C14orf160,L2HGA,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,L2HGDH

Molecular Weight: 48kDa/50kDa

Gene ID: 79944

UniProt: Q9H9P8