KDM4B antibody

Catalog No. ABIN7268329

This Rabbit Monoclonal antibody specifically detects KDM4B in WB, IF and IP. It exhibits reactivity toward Human.

Quick Overview for KDM4B antibody (ABIN7268329)

Target: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This KDM4B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-KDM4B Antibody

Purpose: KDM4B/JMJD2B Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human KDM4B/JMJD2B

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for KDM4B

Target: KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))

Alternative Name: KDM4B

Background: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.,JMJD2B, TDRD14B,Cell Biology & Developmental Biology,Cell Cycle,DNA Damage & Repair,Epigenetic writers and erasers of core Histones,Epigenetic writers and erasers of core Histones_Demethylation,Epigenetics & Nuclear Signaling,Immunology & Inflammation,Kinase,Kinase_Serine/threonine kinases,Nuclear Receptor Signaling,Signal Transduction,KDM4B

Molecular Weight: 150kDa

Gene ID: 23030

UniProt: O94953

Pathways: Warburg Effect