LPAR1 antibody

Catalog No. ABIN7268334

This anti-LPAR1 antibody is a Rabbit Monoclonal antibody detecting LPAR1 in WB. Suitable for Human.

Quick Overview for LPAR1 antibody (ABIN7268334)

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This LPAR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LPAR1 Antibody

Purpose: EDG2/LPA-1 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human EDG2/LPA-1

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for LPAR1

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Alternative Name: LPAR1

Background: The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene [provided by RefSeq, Jul 2008],EDG2, GPR26, Gpcr26, LPA1, Mrec1.3, VZG1, edg-2, rec.1.3, vzg-1,Cancer,Cardiovascular,Cardiovascular diseases,Cardiovascular diseases_Heart disease,Endocrine & Metabolism,G protein signaling,G protein signaling_G-Protein-Coupled Receptors(GPCR),Heart,Immunology & Inflammation,Signal Transduction,LPAR1

Molecular Weight: 39kDa

Gene ID: 1902

UniProt: Q92633

Pathways: Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration