MRI1 antibody (AA 1-369)

Catalog No. ABIN7268499

This anti-MRI1 antibody is a Rabbit Polyclonal antibody detecting MRI1 in WB. Suitable for Human.

Quick Overview for MRI1 antibody (AA 1-369) (ABIN7268499)

Target: MRI1 (Mri1) (Methylthioribose-1-Phosphate Isomerase 1 (Mri1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRI1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRI1 Antibody

Binding Specificity: AA 1-369

Purpose: MRI1 Rabbit pAb

Sequence: MTLEAIRYSR GSLQILDQLL LPKQSRYEAV GSVHQAWEAI RAMKVRGAPA IALVGCLSLA VELQAGAGGP GLAALVAFVR DKLSFLVTAR PTAVNMARAA RDLADVAARE AEREGATEEA VRERVICCTE DMLEKDLRDN RSIGDLGARH LLERVAPSGG KVTVLTHCNT GALATAGYGT ALGVIRSLHS LGRLEHAFCT ETRPYNQGAR LTAFELVYEQ IPATLITDSM VAAAMAHRGV SAVVVGADRV VANGDTANKV GTYQLAIVAK HHGIPFYVAA PSSSCDLRLE TGKEIIIEER PGQELTDVNG VRIAAPGIGV WNPAFDVTPH DLITGGIITE LGVFAPEELR TALTTTISSR DGTLDGPQM

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human MRI1 (NP_001026897.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for MRI1

Target: MRI1 (Mri1) (Methylthioribose-1-Phosphate Isomerase 1 (Mri1))

Alternative Name: MRI1

Background: This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD).,MRI1,M1Pi,MRDI,MTNA,Ypr118w,Epigenetics & Nuclear Signaling,Signal Transduction,Endocrine & Metabolism,Nucleotide metabolism,MRI1

Molecular Weight: 34kDa/39kDa

Gene ID: 84245

UniProt: Q9BV20

Pathways: Methionine Biosynthetic Process